Major pharmacy retailers pull heartburn medication Zantac and other generic versions from shelves after FDA detects carcinogens in samples of drug

Major pharmacy retailers pull heartburn medication Zantac and other generic versions from shelves after FDA detects carcinogens in samples of drug

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Major pharmacy retailers pull heartburn medication Zantac and other generic versions from shelves after FDA detects carcinogens in samples of drug

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AstraZeneca's combo lung disease therapy falls short of FDA approval

AstraZeneca's combo lung disease therapy falls short of FDA approval
Reuters: Health
The U.S. Food and Drug Administration declined to approve AstraZeneca Plc's combo therapy to treat a form of lung disease, the drugmaker said on Tuesday.

Results of GSK and AstraZeneca trials may widen ovarian cancer drug use

Results of GSK and AstraZeneca trials may widen ovarian cancer drug use
Reuters: Health
GlaxoSmithKline and AstraZeneca both reported trial results that will likely make their competing drugs available to a wider group of ovarian cancer patients, possibly helping GSK catch its rival in a highly contested drug class.

Britain's Prince Harry to visit Malawi health centre

Britain's Prince Harry to visit Malawi health centre
Reuters: Health
Britain's Prince Harry will on Tuesday visit a health centre in Malawi before leaving later in the day to join his family in Johannesburg, South Africa.

Malaysia pushes for strict law to police vapes, e-cigarettes

Malaysia pushes for strict law to police vapes, e-cigarettes
Reuters: Health
Malaysia is planning to introduce strict regulations on the sale and use of electronic cigarettes and vaporisers, health officials said on Tuesday, as countries around the world move to ban devices that have been linked to deaths and youth addiction.

Vape shop owners sue Massachusetts over product sale ban

Vape shop owners sue Massachusetts over product sale ban
Reuters: Health
Several vape shop owners are suing the state of Massachusetts for implementing a four-month ban on sales of all vaping products and asked the court to deem it "unconstitutional."

Drugmakers look to use Purdue Pharma's bankruptcy to settle U.S. opioid suits: WSJ

Drugmakers look to use Purdue Pharma's bankruptcy to settle U.S. opioid suits: WSJ
Reuters: Health
Endo International Plc, Johnson & Johnson and other drugmakers that face litigation over the opioid crisis are exploring a way to settle the cases by participating in Purdue Pharma LP's bankruptcy, the Wall Street Journal reported, citing internal documents and a person familiar with the matter.

If you have migraines, put down your coffee and read this

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During medical school, a neurologist taught me that the number one cause of headaches in the US was coffee.

That was news to me! But it made more sense when he clarified that he meant lack of coffee. His point was that for people who regularly drink coffee, missing an early morning cup, or even just having your first cup later than usual, can trigger a caffeine withdrawal headache. And considering how many daily coffee drinkers there are (an estimated 158 million in the US alone), it’s likely that coffee withdrawal is among the most common causes of headaches.

Later in my neurology rotation, I learned that caffeine is a major ingredient in many headache remedies, from over-the-counter medicines such as Excedrin and Anacin, to powerful prescription treatments such as Fioricet. The caffeine is supposed to make the other drugs in these combination remedies (such as acetaminophen or ibuprofen) work better; and, of course, it might be quite effective for caffeine-withdrawal headaches.

But then I learned that for people with migraine headaches, certain drugs, foods, and drinks should be avoided, as they can trigger migraines. At the top of this list? Coffee.

So, to review: the caffeine in coffee, tea, and other foods or drinks can help prevent a headache, treat a headache, and also trigger a headache. How can this be?

Migraine headaches: Still mysterious after all these years

Migraine headaches are quite common: more than a billion people reportedly suffer from migraines worldwide. Yet, the cause has long been a mystery — and it still is.

Until recently, the going theory was that blood vessels around the brain go into spasm, temporarily constricting and limiting blood flow. Then, when the blood vessels open up, the rush of incoming blood flow leads to the actual headache.

That theory has fallen out of favor. Now, the thinking is that migraines are due to waves of electrical activity spreading across the outer portions of the brain, leading to inflammation and overreactive nerve cells that send inappropriate pain signals. Why this begins in the first place is unknown.

Migraines tend to run in families, so genetic factors are likely important. In addition, chemical messengers within the brain, such as serotonin, may also play a central role in the development of migraines, though the mechanisms remain uncertain.

People prone to migraines may experience more headaches after coffee consumption (perhaps by effects on serotonin or brain electrical activity), but coffee itself, or the caffeine it contains, is not considered the actual cause of migraines. Certain foods or drinks like coffee are thought to trigger episodes of migraine, but the true cause is not known.

A new study about coffee and migraines: how much is too much?

In a new study published in the American Journal of Medicine, researchers (including several from the hospital where I work) asked 98 people with migraines to keep a diet diary that included how often they consumed caffeinated beverages (including coffee, tea, carbonated beverages, and energy drinks). This information was compared with how often they had migraines. Here’s what they found:

• The odds of having a migraine increased for those drinking three or more caffeinated beverages per day, but not for those consuming one to two servings per day; the effect lasted through the day after caffeine consumption.
• It seemed to take less caffeine to trigger a headache in those who didn’t usually have much of it. Just one or two servings increased the risk of migraine in those who usually had less than one serving per day.
• The link between caffeine consumption and migraine held up even after accounting for other relevant factors such as alcohol consumption, sleep, and physical activity.

Interestingly, the link was observed regardless of whether the study subject believed that caffeine triggered their headaches.

One weakness of this study is that the researchers did not actually measure caffeine consumption. Instead, they defined one serving of a caffeinated beverage as 8 ounces of regular coffee, 6 ounces of tea, a 12-ounce can of caffeinated soda, or 2 ounces of an energy drink. But caffeine content in different caffeinated beverages can vary widely. For example, an 8-ounce serving of coffee from Starbucks can have twice the caffeine as a similar-sized serving from a Keurig K-Cup. They also did not include caffeine-containing foods in the study, although such amounts tend to be quite small compared with the beverages studied.

The bottom line

There is a lot about the connection between caffeine consumption and migraine headaches that remains uncertain. Until we know more, it seems wise to listen to your body: if you notice more headaches when you drink more coffee (or other caffeinated beverages), cut back. Fortunately, this latest research did not conclude that people with migraines should swear off coffee entirely.

If you like coffee as much as I do, it may seem unfair that you need to keep drinking it to prevent a headache. And if you’re prone to migraines, it might seem unfair that you have to limit your coffee intake to avoid headaches. Either way, you’d be right.

The post If you have migraines, put down your coffee and read this appeared first on Harvard Health Blog.

Factbox: Vaping-related illness causes 12 U.S. deaths - CDC

Factbox: Vaping-related illness causes 12 U.S. deaths - CDC
Reuters: Health
U.S. health officials are investigating a mysterious vaping-related respiratory illness that has so far caused 12 deaths and sickened 805 people.

East Timor moves to contain African swine fever outbreaks

East Timor moves to contain African swine fever outbreaks
Reuters: Health
East Timor is imposing restrictions on the movement of livestock to contain African Swine flu, its agriculture ministry said on Monday after reporting multiple outbreaks to the World Organization for Animal Health (OIE).

Crock Pot (or Instant Pot) Meatloaf Recipe

Crock Pot (or Instant Pot) Meatloaf Recipe

Reading Time: 3 minutes Meatloaf may not jump to mind as a healthy food, but consider this: It’s the perfect way to sneak in some nutritious ground organ meats like liver without anyone noticing. Shhh… don’t tell my kids! This recipe doesn’t include the liver, but is a great versatile base recipe that works in the slow cooker or …

Continue reading Crock Pot (or Instant Pot) Meatloaf Recipe...

September 30, 2019 at 05:30PM Wellness Mama® https://ift.tt/2hMTHxr https://ift.tt/eA8V8J

Optimism is associated with a lower risk of cardiovascular events and mortality, suggests new research (n=229,391) even after taking into account depression, education, and physical activity, suggesting that the promotion of optimism and reduction in pessimism may be important for preventive health.

Optimism is associated with a lower risk of cardiovascular events and mortality, suggests new research (n=229,391) even after taking into account depression, education, and physical activity, suggesting that the promotion of optimism and reduction in pessimism may be important for preventive health.

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Optimism is associated with a lower risk of cardiovascular events and mortality, suggests new research (n=229,391) even after taking into account depression, education, and physical activity, suggesting that the promotion of optimism and reduction in pessimism may be important for preventive health.

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Optimism is associated with a lower risk of cardiovascular events and mortality, suggests new research (n=229,391) even after taking into account depression, education, and physical activity, suggesting that the promotion of optimism and reduction in pessimism may be important for preventive health.

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East Timor reports African swine fever outbreaks

East Timor reports African swine fever outbreaks
Reuters: Health
East Timor reported outbreaks of African swine fever last week, the first occurrence near its border with giant neighbor Indonesia of a virus that killed millions of pigs around Asia, the World Organization for Animal Health (OIE) said.

Alzheimer's memory loss reversed by new head device using Transcranial Stimulation

Alzheimer's memory loss reversed by new head device using Transcranial Stimulation

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Alzheimer's memory loss reversed by new head device using Transcranial Stimulation

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Alzheimer's memory loss reversed by new head device using Transcranial Stimulation

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AstraZeneca, Merck ovarian cancer treatment improves progression-free survival

AstraZeneca, Merck ovarian cancer treatment improves progression-free survival
Reuters: Health
AstraZeneca Plc and Merck & Co Inc said on Monday their treatment for newly diagnosed advanced ovarian

GlaxoSmithKline's cancer therapy cuts risk of disease progression or death by 38%

GlaxoSmithKline's cancer therapy cuts risk of disease progression or death by 38%
Reuters: Health
GlaxoSmithKline plc said on Monday its maintenance therapy for a form of ovarian cancer reduced the risk of disease progression or death by 38% in a late-stage study in cancer patients.

AstraZeneca, Merck cancer treatment attains meaningful improvement in progression-free survival

AstraZeneca, Merck cancer treatment attains meaningful improvement in progression-free survival
Reuters: Health
AstraZeneca Plc and Merck & Co Inc said on Monday their drug to treat a form of ovarian cancer improved progression-free survival in patients tested in a late-stage study.